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Pharmacogenetic testing: A waste of time for predicting response

Pharmacogenetic testing: A waste of time for predicting response

by Nassir Ghaemi | Aug 29, 2023 | Curbside Consults

Q: I was wondering if you’ve used genetic testing to help choose an antidepressant. I have one patient who is requesting it but hasn’t actually “failed” any antidepressant trials. She doesn’t like the idea of waiting several weeks just to...
Lithium orotate over the counter for bipolar illness?

Lithium orotate over the counter for bipolar illness?

by Nassir Ghaemi | Aug 16, 2023 | Curbside Consults

Q: I have a question about Lithium Orotate 10 mg or other low dose. I have a few patients who cannot accept their manic depressive diagnosis but they would accept Lithium Orotate OTC low dose. I suggested it to one after doing the usual labs and EKG. She said it is...
Pleae dose lithium just once daily – Really.

Pleae dose lithium just once daily – Really.

by Nassir Ghaemi | Jul 3, 2023 | Curbside Consults

Question: Dr. Ghaemi recommends Lithium once daily dosing over twice daily to minimize renal side effects, based on studies like this one: Singh, Lokesh Kumar, et al. “Improving tolerability of lithium with a once-daily dosing schedule.” American Journal...
Curbside Consult: Spontaneous remission in bipolar illness

Curbside Consult: Spontaneous remission in bipolar illness

by Nassir Ghaemi | Jan 30, 2023 | Curbside Consults

Q. I saw a patient this week for an initial evaluation who has a historical diagnosis of bipolar disorder (likely type II). She was initially diagnosed while in graduate school at age 28, and experienced what was deemed to be a hypomanic episode, in the midst of her...
Curbside consult: Antidepressant-withdrawal mania

Curbside consult: Antidepressant-withdrawal mania

by Nassir Ghaemi | Jan 30, 2023 | Curbside Consults

Q. I have an 18 year old female with a history of depression who had been stable on citalopram. She had never had a manic/hypomanic episode. She complained of diminished libido and chose to switch to bupropion rather than add a medication to address it. We decided to...
QA:  The “Treatment Overlap” speech and giving an ultimatum in clinical care

QA: The “Treatment Overlap” speech and giving an ultimatum in clinical care

by Nassir Ghaemi | Jan 9, 2023 | Curbside Consults

Question: If you see a new patient and you’re recommending discontinuation of amphetamines due to side effects (like high anxiety) and it leads to patients considering discontinuing care with you, how much will you work with them and prescribe for the time...
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  • Carbamazepine: The most overlooked mood stabilizer
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  • Pleae dose lithium just once daily – Really.

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