by Nassir Ghaemi | Jan 21, 2022 | Blog posts
The conventional wisdom: STAR*D for depression The second large canon of psychopharmacology is the STAR*D study, a large sequential large randomized clinical trial (RCT) of over 1000 patients with an acute depressive episode of so-called major depressive disorder...
by Nassir Ghaemi | Jan 12, 2022 | Blog posts
The conventional wisdom: CATIE for schizophrenia Here is the official line on the design and results of this study: CATIE was a one year study of schizophrenia, in which a large sample of about 1500 patients were recruited at about 50 clinical trial sites (exact...
by Nassir Ghaemi | Jan 11, 2022 | Blog posts
In the mid-1990s, an incredible thing happened. The National Institute of Mental Health (NIMH) decided to fund major clinical psychopharmacology studies. About 90% of NIMH is for other purposes, so the world of clinical psychopharmacology always has suffered from...