Lithium: The Most Effective Drug

Separate scientific knowledge from marketing hype in psychiatry with Harvard lecturer Dr. Nassir Ghaemi, MD

These classes took place between December 5-19, 2025. Your enrollment includes access to all session recordings in our Memberkit area, where you can also comment and ask questions beneath each video.

Dr. Ghaemi has been employed in the past at:

Class 1 — Lithium: The Most Effective Drug in Psychiatry

  • – Beyond “Bipolar I”: Learn exactly when lithium should be your first line for recurrent unipolar depression, suicidality, and complex mood temperaments.
  • -Maintenance Data: See the evidence on why it beats antidepressants and anticonvulsants for long-term maintenance—data that is often ignored.

Class 2 — Lithium: The Safest Psychiatric Drug (When Used Correctly)

  • – Stop the Fearmongering: Master specific protocols for daily dosing strategies that maximize safety.
  • – Clinical vs. Numbers: Learn how to titrate based on clinical response rather than chasing arbitrary lab numbers (acute vs. maintenance targets).

  • – Special Populations: Leave with a clear algorithm for monitoring older adults, pregnancy, and medical comorbidities without unnecessary hassle.

Class 3 — Side Effects and Harms Are Much Less Than You Think

  • -Myth vs. Reality: Look carefully at what actually happens to kidneys, thyroid, weight, and cognition over the long term.
  • -Toxicity Management: Learn how to distinguish small lab changes from true toxicity, and when to taper vs. stay on lithium for life.

  • -Risk Communication: Get concrete language and comparative risk numbers to help patients understand the real long-term tradeoffs. 

Join world-renowned psychiatrist Nassir Ghaemi, M.D., for a three-part, 4h masterclasses that bridges the gap between the science of lithium and the practice of lithium.

– The Mission: Move beyond the fearmongering and “Bipolar I” labels to master the most effective drug in psychiatry—the only agent proven to prevent suicide and provide neuroprotection.

    • – Lifetime access: Get instant access to recordings, slide decks, and materials stay permanently in your private member area—so you can review the protocols whenever you need them.

About Dr. Nassir Ghaemi

Nassir Ghaemi MD MPH is a psychiatrist and researcher specializing in depression and bipolar illness. He is Professor of Psychiatry at Tufts Medical Center in Boston, Clinical Lecturer at Harvard Medical School, teaches at the Cambridge Health Alliance.

Formerly employed at Novartis Institutes of Biomedical Research in Cambridge MA, where he lead clinical psychiatry research in early drug discovery. He is author of numerous books including the bestselling A First-Rate Madness: Uncovering the Links between Mental Illness and Leadership, and, most recently, Clinical Psychopharmacology,

He runs a clinical education website, The Psychiatry Letter with thousands of readers over the world. He has published over 300 scientific papers, and serves on the editorial board of numerous journals.